A Novel Method for Diagnosing Chronic Rhinosinusitis based on an Electronic Nose
Title | A Novel Method for Diagnosing Chronic Rhinosinusitis based on an Electronic Nose |
Publication Type | Journal Article |
Year of Publication | 2003 |
Authors | Mohamed E.I., Bruno E., Linder R., Alessandrini M., Di Girolamo A., Pöppl S.J., Puija A., De Lorenzo A. |
Journal | Anales otorrinolaringológicos ibero-americanos |
Volume | 30 |
Issue | 5 |
Pages | 447-57 |
Date Published | 2003 |
Publication Language | eng |
ISSN | 0303-8874 |
Keywords | Adult, Chronic Disease, Electronics, Female, Humans, Male, Rhinitis, Sinusitis |
Abstract | The nasal out-breath of persons with chronic nasal and/or paranasal infections may have characteristic strange odors, which in our experience are in most cases related to bacterial and/or fungal infections of the sinuses. The objective of the present study was to examine nasal out-breath samples from patients with chronic rhinosinusitis (CRS) (with or without polyposis) and healthy control volunteers using the electronic-nose (EN) technology. We developed a simple technique for collecting samples of nasal out-breath in disposable sterile plastic sacks with a tight closing seal. The principal component analysis correctly classified all individual EN patterns for CRS patients and misclassified 2 samples from the healthy controls (80.0% successful classification rate). The artificial neural network analysis correctly classified 60.0% of the patterns of both groups. We believe that the use of methodologies based on EN technology, combined with conventional clinical examinations, may improve the diagnosis of chronic rhinosinusitis. |
PubMed Link | |
Alternate Journal | An Otorrinolaringol Ibero Am |